Clinical Biochemistry jobs

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Job title: Cellular Toxicologist
Location: Stevenage, Hertfordshire

Working model: Onsite

Contract type: PAYE (Inside IR35)

Overview

GSK is a science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. We are on an audacious journey to impact the health of 2.5 billion people over the next decade. Our R&D division is at the forefront of this mission, dedicated to the discovery and development of groundbreaking vaccines and medicines. We are transforming the landscape of medical research by integrating cutting-edge science and technology and harnessing the power of genetics and new data. By fostering a collaborative environment that unites the talents of our people, we are revolutionizing R&D to pre-empt and defeat diseases. Join us in our commitment to uniting science, technology, and talent to get ahead of disease together.

Role Overview

Design and execute innovative in vitro investigative toxicology experiments or technical work programs to support Project Issues with limited supervision. Lead development of new cellular assay formats/techniques for the investigation of mechanisms and translation of organ and cellular toxicities and safety risks to the clinic. Provide high quality data and expert advice within your specialised area, as required.

Key Responsibilities

• Design and execute innovative in vitro investigative toxicology experiments or technical work programs to support Project Issues with limited supervision; work includes study planning, experiment organization, sample preparation, data generation, processing, analysis and reporting.
• Plan next steps based on interpretation of results in collaboration with the Investigative Lead.
• Lead development of new cellular assay formats/techniques (from tissues, primary cells, or cell culture systems) for the investigation of mechanisms and translation of organ and cellular toxicities and safety risks to the clinic, including routine mammalian cell screening assays.
• Provide high quality data, acceptable to appropriate principles of data integrity (DI), including quality control (QC) of study data.
• Provide expert advice to Project Teams, advisory Safety Panels, Target Safety Reviews and external partners etc within your specialised area, as required.
• Where needed understand the disease target under investigation, and if applicable the therapeutic area, and the programme/project plan and potential safety issues of assigned projects / studies.
• Collaborate with all areas involved in a study to optimise study efficiency and quality to meet project goals and timelines.
• Prepare detailed oral or written reports and interim summaries within agreed timelines.
• Ensure clear, concise timely communication, and provide accurate information to study / report tracking system(s).
• May take a leadership role for specific enabling functions such as safety, facilities, compliance or data integrity on behalf of the group.
• Participate in collaborations (with internal and external partners) to assist the development and deployment of new approaches to improve the efficiency, prediction, mechanistic understanding, and translation of drug safety risks.
• Ensure compliance with GSK SOPs and Policies, GLP, and data integrity, safety, and animal welfare guidelines.

Skills & Qualifications

We are looking for professionals with these required skills:

• MSc or PhD or equivalent by experience in Cellular biology, Toxicology and/or other related biological science.
• Experience of cellular biology using advanced in vitro cellular systems and investigative studies and their conduct, ideally within a Pharmaceutical or Research Institute setting.
• Subject matter expert for a specific technical area, e.g. certain types of in vitro cellular models, or drug modality (ADC, Oligo, Small molecule, etc).

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Inclusion at GSK

GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

If you need any adjustments in the recruitment process, please get in touch with our Recruitment team (EMEA-GSKLink@allegisglobalsolutions.com) to further discuss this today.

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