Python jobs in Manchester

Help build one of the world’s first AI-driven output checking systems for health research.

At UK Biobank, we’re developing new technologies that will help researchers safely access and use some of the world’s richest biomedical datasets.

This role sits within a team building what is believed to be the world’s first automated output checking system for trusted research environments using AI and cloud-native technologies to help ensure researchers can only export files regarded as safe.

It’s a rare opportunity to work on something genuinely new, technically challenging, and mission-driven.

Can you do it?

You’ll join a growing engineering team focused on developing and integrating the Automated Output Checking System across UK Biobank’s internal and external research platforms.

Working across backend services, frontend applications, APIs, and cloud infrastructure, you’ll help build secure and scalable integrations between access management systems, research analysis platforms, trusted research environments, and supplier-built services.

This role combines full-stack engineering, cloud technologies, and emerging AI-driven approaches, giving you exposure to modern system design while contributing to technology that supports global research.

You will be responsible for:

• Building and maintaining scalable, secure, cost-efficient and maintainable full-stack applications using Python (backend) and TypeScript (frontend), including relational and non-relational database management systems on AWS.
• Developing responsive and accessible user interfaces using modern front-end frameworks (e.g., React with TypeScript)
• Assisting in implementing CI/CD pipelines and automated deployment processes
• Ensuring appropriate logging, monitoring, and basic observability are implemented within developed components.
• Participating in development of AI-driven validation and rule-based decision logic under guidance

Is this you?

To be successful, you will have experience in:

• Full-stack software development within a product or delivery team
• Developing backend development using Python frameworks such as FastAPI, Flask, or similar
• Frontend applications using TypeScript and frameworks such as React or Vue
• Working with cloud platforms, preferably AWS
• Microservices and API-based architectures
• SQL and/or NoSQL databases

Working hours are 35 hours per week, Monday to Friday, with some flexibility, 2 days onsite with hybrid working available. Located in Greater Manchester (initially based in Stockport with a move to Manchester Science Park mid to late 2026).

Our passion for diversity and equality means creating a work environment for all employees that is welcoming, respectful, engaging, and enriched with opportunities for personal and professional development.

We actively welcome applications from people with disabilities, long-term health conditions, neurodivergent candidates, and those with diverse thinking styles. We are committed to making reasonable adjustments throughout our recruitment process and in the workplace so that everyone can perform at their best. If you require any adjustments during the recruitment process, please contact Tommy Wilson at jobs@ukbiobank.ac.uk so we can support you

Your Wellbeing Matters to Us

Our wellbeing score on Indeed is rated as 77% (High), reflecting how people experience working here day-to-day. Colleagues often highlight a strong sense of purpose, supportive team culture, and the opportunity to grow.

There’s a real focus on learning, flexibility, and feeling valued, whether that’s developing new skills, contributing ideas, or building a career within Data & Technology.

Benefits

26 Days’ Annual Leave – Plus Bank Holidays
Holiday Buy Scheme
Birthday Leave
USS Pension Scheme
Healthcare Cash Plan
Enhanced Family Leave
Cycle to Work Scheme
Season Ticket Loan
Professional Subscriptions
£500 annual training budget
️Free On-Site Gym
️Subsidised Canteen Lunches
Free Car Parking
️Employee Discounts Portal
Employee Assistance Programme
Annual Flu Vaccination
️Life Assurance Cover

#LI-Hybrid

About UK Biobank
UK Biobank is a large-scale biomedical database and research resource containing in-depth genetic and health information from half a million UK participants.

The database, the largest and most comprehensive of its kind in the world, is anonymised and made widely accessible by UK Biobank to global researchers who use it to find new scientific discoveries about common and life-threatening diseases – such as cancer, heart disease and stroke which strike in mid-later life.

UK Biobank is an innovative organisation with over 350 staff across four sites in the UK that fosters an engaging environment and supports the development of our staff. Our dedicated teams work alongside the world's leading biomedical scientists in our joint mission to improve public health.

Pay: £50,000.00-£60,000.00 per year

Work Location: Hybrid remote in Stockport SK3