High-paying nursing jobs in Manchester
Nursing encompasses the care and support provided by trained professionals to promote health and assist those in need of medical attention. Nurses play a critical role in patient care by assessing conditions, administering treatments, and educating patients and their families. Successful nurses possess strong communication, empathy, and problem-solving skills.
The 135 nursing jobs listed below pay well, with salaries between £30,620 and £43,415 per year. Registered Nurse, Nurse Practitioner and Nurse are among the most popular high-paying roles in Manchester.
Job title
Updated Sept 21, 2026
Job title
Manchester, ENG
England
Job postings (Manchester)
Learning Disability Nurse
Manchester
£43,415
per year
England
£41,377
per year
Nurse Practitioner
Manchester
£43,125
per year
England
£44,805
per year
Nurse
Manchester
£38,837
per year
England
£40,212
per year
Registered Mental Health Nurse
Manchester
£37,164
per year
England
£39,006
per year
Registered Nurse
Manchester
£30,620
per year
England
£37,631
per year
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Learning Disability Nurse
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Please refer to the employers job description for complete details.
Learning Disability Nurses support individuals with learning disabilities by planning care, promoting independence, and liaising with families and professionals. They need expertise in person-centred care, knowledge of developmental conditions, and strong communication skills.
See 6 jobAverage wage
Manchester
£43,415 per yearEngland
£41,377 per year -
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners diagnose illnesses, prescribe treatments, and provide patient education to manage health conditions independently. They need clinical assessment skills, knowledge of healthcare guidelines, and the ability to communicate complex information clearly.
See 21 jobAverage wage
Manchester
£43,125 per yearEngland
£44,805 per year -
Nurse
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Please refer to the employers job description for complete details.
Nurses assess patient health, administer treatments, and support recovery with compassionate care. They need clinical knowledge, patient assessment skills, and effective communication to coordinate care and respond to medical needs efficiently.
See 14 jobAverage wage
Manchester
£38,837 per yearEngland
£40,212 per year -
Registered Mental Health Nurse
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Please refer to the employers job description for complete details.
Registered Mental Health Nurses assess patient needs, develop care plans, and support emotional wellbeing in various settings. They need proficiency in mental health nursing practice, understanding of psychosocial interventions, and effective communication skills.
See 12 jobAverage wage
Manchester
£37,164 per yearEngland
£39,006 per year -
Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses deliver comprehensive patient care, administer treatments, and coordinate with healthcare teams to support recovery. They need clinical nursing knowledge, proficiency in patient assessments, and strong communication skills to ensure effective care and safety.
See 82 jobAverage wage
Manchester
£30,620 per yearEngland
£37,631 per year