High-paying nursing jobs in Manchester
Nursing encompasses the care and support provided by trained professionals to promote health and assist those in need of medical attention. Nurses play a critical role in patient care by assessing conditions, administering treatments, and educating patients and their families. Successful nurses possess strong communication, empathy, and problem-solving skills.
The 122 nursing jobs listed below pay well, with salaries between £30,683 and £49,923 per year. Registered Nurse, Registered Mental Health Nurse and Nurse are among the most popular high-paying roles in Manchester.
Job title
Updated Aug 10, 2026
Job title
Manchester, ENG
England
Job postings (Manchester)
Clinical Lead Nurse
Manchester
£49,923
per year
England
£54,301
per year
Nurse
Manchester
£38,781
per year
England
£40,089
per year
Nurse Assessor
Manchester
£38,184
per year
England
£39,679
per year
Registered Mental Health Nurse
Manchester
£36,947
per year
England
£38,980
per year
Registered Nurse
Manchester
£30,683
per year
England
£37,729
per year
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Clinical Lead Nurse
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Please refer to the employers job description for complete details.
Clinical Lead Nurses oversee patient care standards, coordinate nursing teams, and ensure compliance with healthcare policies. They need expertise in clinical practice, strong leadership skills, and a solid understanding of NHS guidelines and patient safety.
See 14 jobAverage wage
Manchester
£49,923 per yearEngland
£54,301 per year -
Nurse
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Please refer to the employers job description for complete details.
Nurses assess patient health, administer treatments, and support recovery with compassionate care. They need clinical knowledge, patient assessment skills, and effective communication to coordinate care and respond to medical needs efficiently.
See 16 jobAverage wage
Manchester
£38,781 per yearEngland
£40,089 per year -
Nurse Assessor
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Please refer to the employers job description for complete details.
Nurse Assessors evaluate patient care needs, ensure compliance with health standards, and advise on service improvements. They need clinical nursing experience, knowledge of care regulations, and strong assessment and communication skills within health care settings.
See 5 jobAverage wage
Manchester
£38,184 per yearEngland
£39,679 per year -
Registered Mental Health Nurse
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Please refer to the employers job description for complete details.
Registered Mental Health Nurses assess patient needs, develop care plans, and support emotional wellbeing in various settings. They need proficiency in mental health nursing practice, understanding of psychosocial interventions, and effective communication skills.
See 17 jobAverage wage
Manchester
£36,947 per yearEngland
£38,980 per year -
Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses deliver comprehensive patient care, administer treatments, and coordinate with healthcare teams to support recovery. They need clinical nursing knowledge, proficiency in patient assessments, and strong communication skills to ensure effective care and safety.
See 70 jobAverage wage
Manchester
£30,683 per yearEngland
£37,729 per year